Sunderland's Jermain Defoe should be fit after missing the midweek EFL Cup win over QPR with a calf strain.
Goalkeeper Vito Mannone, midfielder Seb Larsson and forward Fabio Borini are all long-term absentees for the Black Cats.
Crystal Palace will be without defender and top scorer Scott Dann, who has a hamstring strain.
James Tomkins is fit despite limping off at half-time against Stoke last weekend with a knee injury.
MOTD COMMENTATOR'S NOTES
Alistair Mann: "Sunderland supporters are now accustomed to their side starting a new season in miserable form. They've not witnessed a league victory in either August or September since 2012!