Southampton manager Ralph Hasenhuttl says there is a "possibility" that Danny Ings could make his return from a hamstring injury.
Ryan Bertrand, Oriol Romeu and Will Smallbone remain sidelined by injuries.
Crystal Palace defenders James Tomkins and Nathaniel Clyne are fit again and hoping to be involved, while Nathan Ferguson is nearing a return.
MATCH FACTS
Head-to-head
- Southampton are winless in their last three games against Crystal Palace at St Mary's (D2, L1).