Manchester United will hope to keep their hopes of finishing in the top four alive when they face 19th-place Watford at Old Trafford.
United occupy fourth place but Arsenal moved to within a point of them with two games in hand following their comeback win over Wolves on Thursday night.
Roy Hodgson's men, meanwhile, are four points off safety and suffered a damaging result against Crystal Palace this week.
Follow Sportsmail's TOBY MILES for live Premier League coverage of Manchester United vs Watford, including build-up, team news and updates.
We'll also have live updates from the other 3pm kick-offs, with Brentford taking on Newcastle in a six-pointer, Brighton vs Aston Villa and Crystal Palace facing Burnley at Selhurst Park.