Crystal Palace may be without up to 11 players through injury but Joe Ledley returns after the birth of his son.
James McArthur is doubtful with a back problem, but Scott Dann, Patrick van Aanholt and James Tomkins are out.
Goalkeeper Emiliano Martinez will start for Arsenal as Petr Cech and David Ospina miss out with respective calf and back injuries.
Midfielder Francis Coquelin returns after missing the win over West Ham due to personal reasons.
Laurent Koscielny misses his second game with an Achilles issue, but he is expected back soon.
WHAT THE MANAGERS SAY
Crystal Palace manager Sam Allardyce: "I can see it going right to the wire, in the end it will be about who can hold their nerve and that is the big key to success when the pressure is on you at this level.