Villa left-back Alex Moreno is back in training after hamstring surgery but this game comes too soon for Jacob Ramsey to return from a foot injury.
Diego Carlos' minor hamstring problem will be assessed. Tyrone Mings and Emi Buendia are long-term absentees.
Crystal Palace could be without Marc Guehi, who came off at half-time in England's midweek win over Scotland.
That could mean a debut for central defender Rob Holding, who signed from Arsenal late on transfer deadline day.
MATCH FACTS
Head-to-head
- Aston Villa have lost just one of their 11 Premier League home games against Crystal Palace (W6, D4).