Arsenal expect to welcome back striker Gabriel Jesus, who was absent for the FA Cup defeat against Liverpool with a minor knee problem.
Oleksandr Zinchenko has missed two games due to a calf injury and will be assessed, while Fabio Vieira may be in contention following two months out.
Crystal Palace winger Jesurun Rak-Sakyi could be available after returning to training following a hamstring issue.
Jordan Ayew is at the Africa Cup of Nations and Michael Olise remains out.
MATCH FACTS
Head-to-head
- Crystal Palace have won just five of the 47 league meetings, including only two away: 2-1 at Highbury in 1994 and 3-2 at Emirates Stadium in 2019.