Arsenal are set to have midfielder Thomas Partey available again after a month out with a thigh problem.
Gabriel Martinelli injured his ankle in the warm-up ahead of Saturday's FA Cup tie with Newcastle and will miss out.
Crystal Palace defender Mamadou Sakho is a doubt, having suffered a thigh strain during Friday's FA Cup defeat against Wolves.
LAWRO'S PREDICTION
Arsenal cannot stop winning now - they needed extra time to beat Newcastle in the FA Cup on Saturday but that is four wins in a row in all competitions.
In contrast, Crystal Palace are not on a great run - their win over Sheffield United on 2 January is their only success in their past seven games.