The combine will be held May 30-June 4 at First Niagara Center and HarborCenter.
The 2016 draft will be held at First Niagara Center on June 24 and 25.
Among the top prospects that will be at the combine are Zurich center Auston Matthews and Tappara right wing Patrik Laine, the top two skaters on NHL Central Scouting's ranking of international skaters eligible for the draft.
Matthews, a 6-foot-1, 210-pound native of Scottsdale, Ariz., had 24 goals and 46 points in 36 games in National League A, Switzerland's top professional league. He was second in voting for league MVP and won the league's Rising Star award.