"He told me that I need to be aggressive," Marquez said. "Today, I was aggressive and I hit the release point."
Marquez held the Cubs scoreless until the sixth, when Jason Heyward delivered his second Cactus League homer, a two-run shot.
Lefty Brett Anderson, in line to start the Cubs' fourth regular-season game, held the Rockies to an unearned run and six hits in four innings. The only run was on a Trevor Story single in the third to drive in DJ LeMahieu, who reached on an error.
"My body feels good," said Anderson, whose next outing will be an exhibition vs.