Right-hander Raisel Iglesias started for the Reds and pitched three innings, allowing four hits and three runs, all on the Valaika's three-run blast. Reliever Pedro Villarreal allowed Adames' homer.
Brandon Phillips, who sat out the previous three games with a stiff neck, hit his first homer of the spring to lead off the second against Rockies starter Jorge De La Rosa in his first at-bat of the game.
De La Rosa, the Rockies' Opening Day starter, worked six innings, allowing four runs on nine hits with two walks, three strikeouts and a wild pitch.