During the offseason, 2,880 human beings (32 teams x 90 players) can be rostered by an NFL team. Once Week 1 rolls around, that number is cut down to 1,696 (32 x 53). The ESPN Fantasy player database includes nearly 2,500 players.
You can't be expected to know all of those players, which is why "The 192" is here to make your life easier.
Why 192? Fantasy leagues come in all shapes in sizes, but many have settled into leagues featuring 12 teams and 16 players.