The Colorado Avalanche top three line combinations and top two defensive pairings seem pretty well set:
Alex Tanguay–Matt Duchene–Jarome Iginla
Gabriel Landeskog–Carl Soderberg–Nathan MacKinnon
Blake Comeau–John Mitchell–Mikhail Grigorenko
Erik Johnson–Francois Beauchemin
Naturally, that could change at any time — including mid-game on opening night.