Centeno, who had four career home runs in 1,665 Minor League plate appearances, and none in the Majors prior to Saturday, came through against Kluber in the fifth inning to give Minnesota a 2-1 lead it would not relinquish. Eddie Rosario knocked in another run with a groundout in the sixth and Eduardo Nunez added a run-scoring sacrifice fly in the seventh to pad the Twins' lead.
Centeno also doubled and scored within the Twins' two-run ninth, ending the day 2-for-3 with two runs, two RBIs and one walk.
It was a sufficient showing to support Santana (1-2), who yielded only one run on five hits in six innings of work for Minnesota.