The Cleveland Indians were facing a serious problem when Michael Brantley headed back to the disabled list in early May.
The outfield lost perhaps its best player, leaving players like Marlon Byrd and Tyler Naquin to pick up the slack. Then June rolled around, and Byrd was suspended 162 games for PEDs, effectively ending his career.
This situation was brought on in part by the absence of Abraham Almonte, who was out until July 3 while serving a PED suspension of his own. His return came in a 17-1 loss to the Toronto Blue Jays, which may have been karma for his use of banned substances.