According to ESPN, Clemson will enter their 8pm ABC home game against Notre Dame without their starting center.
Against Louisville, Norton was held out with a sprained knee. Additionally, Joe Gore briefly left the game and Jake Fruhmorgen got banged up. Fortunately, both Gore (sore ankle) and Fruhmorgen (PCL) should be good to go.
Jay Guillermo will once again start at center. He performed admirably and we do not expect any drop off in play from Norton to Guillermo, however the Tigers depth is being challenged. He'll need to stay healthy and carry the load for the time being.