If you are unfamiliar, the Associated Press (AP) hands out both an offensive player of the year and defensive players of the year, and Clemson football has never had a winner from either category.
From the offensive side, no offensive linemen have ever won the award, so John Simpson and Tremayne Anchrum realistically have no shot, but Tee Higgins will. Only nine receivers have ever won the award, which started in 1967. The last receiver to do so was Odell Beckham Jr.in 2014 when he was with the New York Giants.