David Holmberg didn’t allow a hit until the fourth inning. Then out of the nowhere, the no-hitter, and the 1-0 lead were gone. Justin Upton smoked a 2-2 pitch for a home run to right-center, and the Padres took a 2-1 lead. Holmberg did give the Reds his best performance of his young career, as he only allowed those two runs through 6.2 innings. Pedro Villarreal got Holmberg out of a bases loaded jam with two outs in the seventh inning.
Earlier in the game, Jay Bruce hit his 200th career home run in the top of the second to give the Reds a 1-0 lead.