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How to Watch: San Francisco Giants at Cincinnati Reds on Opening Day

The Cincinnati Reds begin their quest to take the baseball world by storm in 2025 by first hosting the San Francisco Giants, long ago their rivals in the NL West. 4:10 PM ET on Thursday, March 27th in Great American Ball Park is the time and place to catch the first pitch of the season, with the rest of the series picking back up on Saturday and culminating Sunday afternoon.

The Giants enter year two of the Bob Melvin Era, the manager leading the club to a disappointing 80-82 record in 2024 that resulted in a major overhaul within the organization at season’s end.