RHP Erick Fedde made his 15th start of the season, ninth on the road and sixth career against the Arizona Diamondbacks. He went 6.0 IP with 8 hits, 2 runs, 0 walks and 6 strikeouts.
John Brebbia, Steven Wilson and Tanner Banks all pitched innings of relief.
Arizona got on the board first as Ketel Marte singled on a ground ball to right fielder Tommy Pham, scoring Corbin Carroll.
In the top of the 3rd inning, Andrew Vaughn tied the game at 1 with an RBI single, driving in Martín Maldonado. In the following inning, Paul DeJong homered on a fly ball to right center field to give the White Sox the lead, 2–1!