Anything less than another Sox sweep would be an utter disappointment to their fan base, while Cubs fans already have tuned out of this mind-numbing season.
Nevertheless, the games will be played, weather permitting, so here are 11 of the most intriguing matchups on and off the field.
The Sox manager is biding his time before October, making sure everyone gets enough rest (hello, Tim Anderson) and trying to get the bullpen on automatic pilot after another shaky month.