Chicago White Sox (4-2)
- NONE
Cleveland Indians (2-2)
- Michael Brantley – RF – 15 Day DL – Michael Brantley is recovering from November 2015 shoulder surgery. Brantley took batting practice on April 2, but was placed on the 15 Day Disabled List on April 3, retroactive to March 25, 2016.
- Lonnie Chisenhall – RF – 15 Day DL – Lonnie Chisenhall is recovering from a left wrist impingement. Chisenhall was placed on the 15 Day Disabled List on April 3, retroactive to March 28, 2016.