Arizona trailed, 3-2, in the seventh when Ildemaro Vargas hit an RBI single and another run scored on an error by left fielder Kyle Schwarber. Oswaldo Arcia added a solo homer in the eighth.
Russell helped the Cubs on defense with a perfect throw in the second. Arizona loaded the bases with two outs against Kyle Hendricks, and two runs scored on Ketel Marte's double to left.