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What are the biggest blowouts in modern MLB history?

In April 2025, the Cincinnati Reds blew out the Baltimore Orioles with an impressive 24-2 rout. The milestone marked the 18th game in the past 125 Major League Baseball seasons with a run differential of 22 or more runs. The Reds' 24 runs were the most scored by any team since the Los Angeles Angels' 25 on the road against the Colorado Rockies on June 24, 2023. On a historical scale, the Reds' result also marked the team's largest margin of victory since a 26-3 win over the Boston Braves in 1911.