Running down the best home-opener moments in Cubs franchise history:
2017 - (April 10, 2017 vs. LAD) World Series Banner Night - Anthony Rizzo walkoff single in bottom of the 9th off Kenley Jansen. Jon Jay scored winning run. First cubs walkoff win in Home Opener since 2000. Cubs win 3-2.
2016 - (April 11, 2016 vs. CIN) Addison Russell go-ahead 3-run HR in bottom of 8th of Jumbo Diaz. Cubs win 5-3.
2000 - (April 10, 2000 vs. ATL) Jeff Reed walk-off single in 9th off Luis Rivera. Damon Buford scores.