Here is the boxscore from the last game these two teams played in Wrigley Field before today.
Just four men who played in that game nearly 11 years ago are still active: Jose Altuve, J.D. Martinez, Jordan Lyles and Anthony Rizzo. One is deceased (Luis Valbuena, who died in a car accident in 2018).
The Cubs won that game 14-6. Rizzo homered for the Cubs. So did Ryan Sweeney, who is now doing studio work for Marquee Sports Network.
That series was the first time the Cubs faced the Astros after their move to the American League.