Game One Hundred Forty-One – Cubs 1, Astros 2
WP – Collin McHugh (10-10) LP – John Lackey (9-8) Save – Ken Giles (10)
John Lackey allowed only two runs in six solid innings and the bullpen kept the Astros from tacking on. The Astros scored on solo home run and a safety squeeze bunt in the third inning. The Cubs managed just one run on a sacrifice fly by Willson Contreras and continued to struggle with runners in scoring position. The Cubs had two hits and lost to the Astros on Saturday afternoon.