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Cubs’ Jeremiah Estrada, Brendon Little debut in 5-3 loss to Blue Jays

TORONTO – Two Cubs relievers made their major-league debuts in the Cubs’ 5-3 loss to the Blue Jays on Tuesday, with quite different results.

Before the game, the Cubs selected right-handed reliever Jeremiah Estrada as their second substitute player in Toronto.

The Cubs had already put pitchers Justin Steele and Adrian Sampson on the restricted list due to Canada’s COVID-19 vaccine requirements for entry. They added lefty reliever Brandon Little as a substitute player on Monday.

Little was the first to debut Tuesday. He replaced starter Marcus Stroman, who held the Blue Jays to one run in five innings.