This picture didn’t come with any information other than what is already obvious (well, to me, at least): Bill Hands is pitching for the Cubs at Wrigley Field. Oh, and one more thing:
Chicago Cubs Bill Hands pitching in game against Expos.
So that’s one clue, the opponent.
Your next clue is on Ernie Banks’ right sleeve. There, you can see the “100TH ANNIVERSARY” patch that all players wore in 1969.
So this is 1969. It’s also got to be early in the season, because the trees visible in the background are bare.