France's Stephanie Frappart will become the first female official to take charge of a men's Champions League game when Juventus host Dinamo Kiev on Wednesday.
Frappart, who turns 37 next month, was the first female referee to officiate in a major UEFA competition match when Liverpool played Chelsea in the Super Cup in Istanbul last year.
She also officiated the 2019 Women's World Cup final between the United States and Netherlands and became the first female referee to take charge of a French Ligue 1 match when Amiens played Strasbourg in April last year.