Nottingham Forest remained third with a goalless draw against Arsenal as the race for European football took another turn on Wednesday.
Manchester City went back above Chelsea into fourth with a 1-0 win against Tottenham Hotspur, after the Blues had temporarily gone above the champions with a comfortable victory over struggling Southampton on Tuesday.
Brighton went level on points with seventh-placed Bournemouth with a 2-1 win against the Cherries, while Fulham boosted their chances of a European place by beating Wolves at Molineux.
However, there was disappointment for Aston Villa after a 4-1 defeat by Crystal Palace.