Cole Palmer and Ben Chilwell are among four senior players left out of Chelsea's 25-man Conference League squad.
England forward Palmer, midfielder Romeo Lavia and defender Wesley Fofana have been purposely left out to manager their workload.
Chelsea could play about 80 matches this season in five competitions.
The decision was made to rest star man Palmer in the league phase of Europe's third tier competition, with Lavia and Fofana working their way back from long-term injuries.
Chelsea can re-register the trio for the knockout rounds on 6 February when squads can be re-submitted.