Mexico travel to Qatar with a squad predominantly from their homeland and a handful of players plying their trade in Europe.
Edson Alvarez, the combative defensive midfielder, has been linked with big-money moves to the likes of Chelsea and Barcelona and will be an integral part of the side.
While Andres Guardado is gunning for a remarkable record if he takes to the pitch at the World Cup.
Napoli forward Hirving Lozano looks like he will shoulder plenty of attacking responsibility, while Raul Jimenez' form and fitness is a concern.