Manchester City winger Jack Grealish is ruled out after being withdrawn against Copenhagen with a muscle problem.
Bernardo Silva was hurt by a heavy tackle in the same game and will be assessed, while Josko Gvardiol remains out with an ankle injury.
Mateo Kovacic and Sergio Gomez come back into contention after resuming training.
Chelsea are without Thiago Silva, who was forced off against Crystal Palace because of a groin injury.
Fellow defenders Malo Gusto and Levi Colwill are fit despite minor issues in Monday's victory but Carney Chukwuemeka is absent with a twisted ankle.