Atletico and Real will play out one of the biggest Madrid derbies in recent years as Los Blancos attempt to hunt down their rivals at the top of LaLiga.
Diego Simeone's men are the current league leaders after a superb season so far, but their vulnerabilities have been put on full display recently after concerning losses to Chelsea and Levante.
Real, on the other hand, are on a high after winning five of their last six games - they'll be confident of winning at the Wanda Metropolitano and closing the gap.