Holders Chelsea will be without Mason Mount, Christian Pulisic, N'Golo Kante and Reece James for their Champions League game at Juventus on Wednesday.
Chelsea lost 1-0 to Manchester City in the Premier League on Saturday, their first defeat of the season.
Massimiliano Allegri's Juve are four games unbeaten and have moved up to 10th in Serie A after a terrible start.
"They are such a big club," said Blues boss Thomas Tuchel. "Yes they have had some troubles, a rough start but they were very convincing in the Champions League [a 3-0 win at Malmo].
"They are reliable.