Everton captain Seamus Coleman is expected to miss a fourth match as he continues to recover from a recurring hamstring problem.
Fabian Delph has been ruled out with a similar injury, which he sustained against Burnley last weekend.
Chelsea winger Christian Pulisic, who was rested for Tuesday's draw against Krasnodar as a precaution after recent hamstring issues, is available.
Hakim Ziyech and Callum Hudson-Odoi are both sidelined for two weeks.
LAWRO'S PREDICTION
There are question marks over Everton's defence so this is not a good time for them to be playing a Chelsea side who are playing well, scoring plenty of goals and on an unbeaten run of 17 games.