Chelsea have already sealed their place in the round-of-32 in the Europa League, but will now be out to ensure they earn top spot in their penultimate Group L game.
The Blues need only to avoid what would be a shock defeat by PAOK at Stamford Bridge to win the group and ensure they will be one of the seeded teams for when the knockout stages begin in February.
Meanwhile, it is a lot closer in Rangers' group as all four teams are separated by just two points as Steven Gerrard's side chase victory at home to Villarreal at Ibrox.