Chelsea winger Hakim Ziyech could make his first appearance since suffering a hamstring injury in early December.
Defender Reece James will definitely miss the game because of a similar problem.
Kyle Walker and Gabriel Jesus will be absent for Manchester City as they continue to self-isolate following recent positive coronavirus tests.
However, there were no new positive tests when the City squad was tested on Wednesday.
MOTD COMMENTATOR'S NOTES
Steve Wilson: Chelsea and Manchester City have had their bad days but so has everybody else - and City's league position is artificially low because of their games in hand.