Brentford full-back Aaron Hickey will be sidelined until after the World Cup after damaging ankle ligaments in training last week.
A hamstring injury is also likely to keep out captain Pontus Jansson until the top flight resumes on 26 December.
Christian Norgaard and Thomas Strakosha remain unavailable.
Chelsea have no new injury concerns, with Thiago Silva fit despite complaining of hamstring tightness after the win at Aston Villa.
Wesley Fofana, N'Golo Kante and Reece James are all long-term absentees.
CHRIS SUTTON'S PREDICTION
Chelsea got over the line against Aston Villa on Sunday but it felt like they had to grind that one out.