A first half quick double from Brentford set the Bees on their way to a comfortable 3-0 win over Southampton at the Gtech Community Stadium.
Ben Mee and Bryan Mbeumo struck during a three-minute spell, moments from half time and the win was secured in the second half when Mathias Jensen added a third.
The victory sees Thomas Frank's side move into the Premier League top six, above West London rivals Fulham and Chelsea.
Southampton gave debuts to new signings Kamaldeen Sulemana and 6ft '7 Paul Onuachu, but couldn't find a way back into the game.