4:25 p.m. ET | FOX
Matchup rating: 73.1 | Spread: NO -7 (47.5)
What to watch for: Carolina quarterback Teddy Bridgewater's protection will be down to a fifth left tackle (converted guard Michael Schofield). The Saints have one of best pass-rushes in the NFL, ranking eighth in sacks with 42. It could be a long day for Bridgewater, who has struggled under duress. -- David Newton
Bold prediction: Saints running back Alvin Kamara will score fewer than six touchdowns!