The Panthers have placed oft-injured running back Christian McCaffrey on injured reserve, ending his season after he sustained an ankle injury in the Panthers’ Week 12 loss to the Dolphins.
Regardless of how serious McCaffrey’s ankle injury is — and we know it’s at least a 3-week injury or they wouldn’t have placed him on injured reserve ahead of a bye week — the team cannot re-activate him from injured reserve per NFL rules since this is the second time he has been placed on injured reserve this season.
The second stint on IR is an automatic out for the season designation.