As NFL teams prepare for Week 3, injuries have caused adjustments to their depth charts.
The San Francisco 49ers will be without quarterback Trey Lance for the rest of the season after successful ankle surgery on Monday. He suffered a fibula fracture and ligament disruption in Week 2 against the Seattle Seahawks. Backup Jimmy Garoppolo, who led the team to the NFC Championship game last season, will take over under center.
Los Angeles Chargers quarterback Justin Herbert has been nursing a rib cartilage injury he suffered late in last week's game against the Kansas City Chiefs.