Ever seen that movie The Replacements? Totally should. In the meantime let me give you the gist, none of the really good players are available due to a labor dispute, then Keanu Reeves and a bunch of squibs come in and generally stink it up but play with heart. At first blush the average fantasy player might be convinced that just such a thing was taking a place IRL.
Let's do a quick roll call. Romo? Out. Brees? Out. Demarco Murray? MIA in short, nearly every single early round favorite is injured or completely ineffective thus far in the season.