The Carolina Panthers ended last season on a 5-1 straight-up and 3-2-1 against-the-spread run that only ended in a tough NFC playoff loss at eventual conference champion Seattle. Cam Newton and his crew hope to carry that momentum over to this season when they visit Jacksonville for a battle of big cats on Sunday.
Point spread: Panthers opened as 2.5-point favorites; the total was 43.5 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 22.