The Panthers look to lose Andrew Norwell and perhaps Star Lotulelei in the upcoming free agency period. Losing one of the best guards in the game and one of the best pieces of a shoddy offensive line will surely sting.
However, I believe second-year lineman Taylor Moton will be able to fill in quite admirably at left guard in Nowell's wake. The real questions are at center, defensive end, wide receiver, and depth in the secondary.
Though you can expect the Panthers to be active in Free Agency this year under a new regime; they will need to have a good draft if they want to make a deeper playoff run this year.