Tottenham's Serge Aurier could feature after five games out but Giovani Lo Celso remains a few weeks away from a return after a hamstring injury.
The likes of Harry Kane and Son Heung-min, who were rested for the midweek Europa League game, are set to return.
Burnley's Ashley Barnes is ruled out with a thigh injury but Robbie Brady could return.
Erik Pieters, Chris Wood and Dale Stephens are also in contention and will be given late fitness tests.
LAWRO'S PREDICTION
Both of these sides have been out of sorts recently, although Tottenham did get a good result in the Europa League on Wednesday.