Burnley could hand debuts to summer signings such as James Trafford, Zeki Amdouni, Sander Berge and Dara O'Shea.
Michael Obafemi, who has joined after a loan spell at Turf Moor last season, is ruled out with a hamstring issue.
Manchester City boss Pep Guardiola says Croatia centre-back Josko Gvardiol is available for his first appearance after joining from RB Leipzig for £77m.
Fellow defender Nathan Ake is fit despite missing the Community Shield against Arsenal with a minor injury.
Midfielder Mateo Kovacic could make his league debut for City after moving from Chelsea in June for an initial £25m.