Charlie Taylor sustained a hamstring problem against Sheffield United on Tuesday and could be among a lengthy list of Burnley absentees.
Dwight McNeil, Matej Vydra and Jay Rodriguez are also major doubts, while Jack Cork and Johann Berg Gudmundsson are still building up their fitness.
Loanee Mario Lemina is available for Fulham, having been ineligible to face parent club Southampton last time out.
Ivan Cavaleiro could be fit, while Kenny Tete is back in the squad.
The full-back has been out for more than three months with a torn calf and, most recently, due to the birth of his child.