The Sabres have plenty of options on what to do with the #21 pick, and one of them is to address a big organizational weakness.
One of the nice things about having such a big pool of picks and prospects, as Buffalo Sabres general manager Tim Murray does this year, is that large war chest gives him plenty of options on draft day when it comes to the late first round and early second round.
The Sabres could use the pick as part of a package to trade for, say, a young goaltender, or for an established top-6 veteran with a big contract that another team can't afford to pay.